I suppose it could be possible, it sounds like they are trying to eat the algae off the silicone and lost silicone is simply a by product. i notice my plecos running up and down the seams, ive not paid much attention to them.
if you are doing your own resealing make sure to find the aquarium type, otherwise if you are worried about the fish health silicone is pretty neutral it should pass right through.
others correct me if im wrong but a tank can still be of good/sound construction with only the seal between the glass.